A layover of more than 6 hours at the airport can get a little boring, so you may be thinking about leaving for a short excursion! If you are, definitely consider just how much time you have, which country or city you are in, and how much time it will take to get to and from the airport.
You will have to go through those long security lines again and you may also have to collect and re-check your baggage. If you're in a foreign country, you will have to pass through customs and you may need a visa to leave the airport.
Be sure to plan ahead and, when you're at the airport, speak to an agent for any assistance.